Effects on Pain, Stress, Anxiety, Physical and Mental Performance, Vitality and (Indirect) Longevity Markers
PART 1
Executive Summary
The Importance of Musculoskeletal and Neuromuscular Health
Healthy aging and peak performance depend on more than aerobic fitness or strength alone. Across the lifespan, muscle mass, neuromuscular coordination, joint function, and balance determine how effectively people move, work, and recover. In older adults and clinical populations, declines in strength and function drive:
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Increased pain and disability
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Higher risk of falls and injury
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Reduced independence and quality of life
In athletes and active individuals, insufficient neuromuscular conditioning, poor balance, and impaired recovery limit performance and increase injury risk.
Interventions that can simultaneously improve strength, function, and pain, while being accessible to frail or deconditioned individuals, have high value for both clinical care and performance optimization.
How Full-Body Vibration Works
Full-body vibration (FBV, also called whole-body vibration, WBV) involves standing, sitting, or performing exercises on a platform that oscillates at specific frequencies (2–45 Hz) and amplitudes (0.44–20 mm).
Key features across the included studies:
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Vibration parameters
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Frequency: typically 2–45 Hz
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Amplitude: 0.44–20 mm
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Sessions: often 5–10 × 1-minute bouts, or 4–10 minutes total/session
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Frequency of sessions: commonly 2–3×/week, sometimes up to 5×/week
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Duration of interventions: from 4–6 weeks to 12 weeks and up to 1 year
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Body position & loading
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Standing with slight knee flexion
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Static or dynamic squats, lunges, trunk exercises
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Occasionally combined with strengthening exercises off-platform
The proposed mechanisms include:
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Neuromuscular stimulation – Vibration elicits tonic vibration reflexes, increasing muscle spindle activation and motor unit recruitment.
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Improved muscle strength and power – Repeated short bouts act as a form of neuromuscular training, enhancing force production and coordination.
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Joint stability and proprioception – Oscillations challenge postural control, improving balance and joint position sense.
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Circulation and recovery – Vibration may increase local blood flow and accelerate clearance of metabolites, reducing delayed-onset muscle soreness (DOMS).
Benefits at a Glance
Across randomized controlled trials, quasi-experimental studies, and systematic reviews/meta-analyses, full-body vibration therapy demonstrates:
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Pain and Musculoskeletal Outcomes
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In chronic musculoskeletal pain, knee osteoarthritis, and fibromyalgia, WBV reduces pain with standardized mean differences (SMDs) around –0.67 to –0.78 in meta-analyses.
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Chronic low back pain trials show substantial reductions in pain (e.g., ~–1 point on VAS) and improvements in disability indices.
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Physical Performance and Strength
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Older men and women show 9.8–13.1% increases in strength and 3.4–3.8% increases in muscle mass after WBV training.
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Athletes and healthy younger adults demonstrate improved jump performance, flexibility, and power output.
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Balance, Gait, and Function
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Frail elderly in residential care and nursing homes exhibit clinically meaningful improvements in Timed Up and Go, Tinetti, 6-minute walk test, and other mobility assessments, with benefits persisting up to 12 months in some studies.
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Older adults with knee osteoarthritis show improved function and gait with effect sizes up to 0.82 for function and strength.
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Mental Health (Stress, Anxiety, Depression)
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Inactive college students and individuals with fibromyalgia report reduced depression, anxiety, and stress scores, alongside improved quality-of-life indices that include vitality subscales.
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Recovery & DOMS
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One study reports a 22–61% reduction in delayed-onset muscle soreness following WBV compared to control conditions.
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Vitality and Quality of Life
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Several studies show improvements in quality-of-life instruments (e.g., SF-36, Fibromyalgia Impact Questionnaire), including vitality domains.
Notably:
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No included studies directly assessed sleep as a primary endpoint.
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No studies directly measured longevity, though some outcomes (e.g., function, balance, vitality) are indirectly related to healthy aging.
Executive Summary Conclusion
Full-body vibration training is a low-impact, scalable intervention that:
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Reduces pain and improves function in patients with knee osteoarthritis, chronic low back pain, and fibromyalgia.
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Enhances strength, power, and mobility in older adults, athletes, and general populations.
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Provides mental health benefits in select populations, including reduced depression, anxiety, and stress.
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Improves quality-of-life and vitality metrics, with a favorable safety profile and high adherence.
While no direct evidence currently supports effects on sleep or lifespan, WBV clearly supports musculoskeletal health, physical performance, and perceived vitality, all of which contribute to healthier aging and better quality of life.
PART 2
Evidence Review Methods
Paper Search
A semantic search was conducted using the query:
“Create a report on the use of full body vibration looking at helping with sleep, pain, stress, anxiety, physical and mental performance, pain, longevity, and vitality.”
The search covered more than 126 million academic papers via the Elicit engine, which aggregates content from Semantic Scholar and OpenAlex.
From this corpus, the 500 most relevant papers were retrieved for screening.
Screening
We included studies that met all of the following criteria:
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Whole-Body Vibration Intervention
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The intervention consisted of full-body vibration delivered via a platform or similar device influencing the whole body (not localized vibrotherapy to a single limb or muscle).
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Primary Outcomes of Interest
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Sleep quality/quantity
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Pain intensity or musculoskeletal symptoms
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Stress or anxiety
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Physical performance (strength, power, endurance, mobility, balance)
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Cognitive/mental performance
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Longevity indicators
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Vitality or related quality-of-life measures
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At least one relevant domain was measured:
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Study Design Quality
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Randomized controlled trials (RCTs)
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Quasi-experimental or controlled clinical trials
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Systematic reviews or meta-analyses
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Human Participants
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Human subjects of any age and health status.
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Isolatable WBV Effects
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If WBV was part of a combined intervention (e.g., WBV + exercise), the design allowed the specific effects of vibration to be identified (through comparisons to similar exercise without vibration, or separate WBV arms).
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Publication Quality
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Full research articles only (excluding single-subject designs, case reports, conference abstracts, editorials, and opinion pieces).
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Intervention Duration
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Sustained or repeated WBV exposure beyond single-session acute effects.
A holistic judgment was applied for each paper, balancing these criteria.
Data Extraction
Using a large language model, we extracted structured data for each included study:
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Population characteristics
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Sample size, age, sex distribution, health status
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Target condition (e.g., knee osteoarthritis, fibromyalgia, chronic low back pain, frail elderly, athletes)
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Setting (residential care, community, outpatient clinic, university, etc.)
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WBV protocol details
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Vibration type (vertical, rotational, etc.) when available
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Frequency (Hz) and amplitude (mm), including progression over time
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Session duration, number of bouts per session
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Weekly session frequency and total program duration
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Body positions (standing, squats, etc.) and co-exercises
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Target outcomes
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Pain, function, strength, balance, gait, mental health, quality of life, vitality, and any sleep-related measures
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Measurement tools and time points (baseline, post-intervention, follow-up)
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Results summary
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Effect sizes (standardized mean differences, percent changes)
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p-values and confidence intervals where available
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Direction of effect (improvement, no change)
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Durability of effects at follow-up
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Control conditions and study quality
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Type of control (sham WBV, exercise without vibration, usual care, no treatment)
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Randomization and blinding procedures when reported
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Dropout rates and adverse events
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Authors’ discussion of limitations and risk of bias
Characteristics of Included Studies
Populations:
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Elderly / older adults: 9 studies (community-dwelling, nursing home, frail elderly)
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Knee osteoarthritis: 4 studies
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Chronic or subacute low back pain: 3 studies
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Fibromyalgia: 5 studies
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Athletes: 2 studies
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Healthy adults: 2 studies
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Other / mixed: inactive college students, untrained men, and several systematic reviews/meta-analyses
Intervention parameters:
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Duration
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12 studies: ≤6 weeks
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10 studies: 7–12 weeks
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6 studies: >12 weeks
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Session frequency
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Most commonly 2–3×/week; some 2–5×/week or 3–5×/week
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Frequency / amplitude
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Frequency: 2–45 Hz (reported in 10 studies)
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Amplitude: 0.44–20 mm (reported in 8 studies)
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Co-exercises
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8 studies combined WBV with additional exercises (e.g., squats, strengthening).
Primary outcomes:
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Pain: 11 studies
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Function / mobility: 19 studies (Timed Up and Go, 6-minute walk, WOMAC)
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Strength / power: 10 studies
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Balance: 8 studies
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Quality of life: 8 studies
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Depression/anxiety/stress: 3 studies
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Other: flexibility, muscle mass, proprioception, endurance.
PART 3
Expanded Explanation of the Benefits of Full-Body Vibration
1. Pain and Musculoskeletal Outcomes
Pain reduction is one of the most consistently reported benefits of WBV in chronic musculoskeletal disorders.
Evidence Summary
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Knee osteoarthritis (KOA)
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Systematic review/meta-analysis (Qiu et al., 2022) of RCTs in KOA shows standardized mean differences in pain and function ranging from 0.46–0.82, favoring WBV for pain reduction, function, and Timed Up and Go performance (p < 0.05).
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Another meta-analysis (Wang et al., 2015) reports SMDs of approximately –0.72 for function and –0.78 for balance, with mixed effects on pain (some analyses not reaching significance).
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Chronic low back pain (CLBP)
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RCTs and systematic reviews indicate WBV can reduce pain intensity and disability. One RCT reported –1.0 points on VAS and –3.81 points on Oswestry Disability Index (p < 0.001) after 12 weeks of WBV.
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A systematic review/meta-analysis of chronic musculoskeletal pain (Dong et al., 2019) reports SMD –0.67 for pain across CLBP, osteoarthritis, and fibromyalgia.
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Fibromyalgia
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Multiple RCTs report significant reductions in pain and fibromyalgia-related impact with 4–12 weeks of WBV combined with exercise, with some benefits sustained up to 6 months (Alev et al., 2017; Sañudo et al., 2010; Mingorance et al., 2021).
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Delayed-onset muscle soreness (DOMS)
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In untrained men, WBV reduced perceived DOMS by 22–61% compared with control conditions (Rhea et al., 2009).
Overall, 10+ studies focus on pain, with standardized mean differences typically in the moderate range (–0.67 to –0.78), representing meaningful symptom relief in chronic pain populations.
2. Physical Performance and Strength
Full-body vibration acts as a neuromuscular training stimulus, especially valuable for populations unable to tolerate high mechanical loads.
Evidence Summary
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Older adults
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In a 1-year RCT, older men experienced 9.8–13.1% strength increases and 3.4–3.8% increases in muscle mass with WBV, comparable to or exceeding fitness training in some parameters.
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Systematic reviews and meta-analyses (Kim et al., 2023; Tan et al., 2023) report moderate effect sizes (SMD 0.54–0.82) for lower limb strength, power, and endurance among older adults.
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Athletes and younger adults
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Female athletes experienced significant gains in knee extensor strength, jump performance, and flexibility after 8 weeks of WBV (Fagnani et al., 2006).
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Healthy adults exposed to 4 months of vertical WBV showed an 8.5% increase in jump height and a 3.7% increase in strength (Torvinen et al., 2002).
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Trunk-muscle training with WBV improved trunk flexor strength and Y-balance performance in university men (Maeda et al., 2016).
In summary, across older adults, clinical populations, and athletes, WBV consistently improves strength, power, and neuromuscular performance, with effect sizes often comparable to traditional resistance training—particularly attractive for populations with mobility limitations.
3. Balance, Gait, and Functional Mobility
Functional mobility, balance, and gait are critical determinants of independence, fall risk, and performance.
Evidence Summary
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Frail elderly & nursing home residents
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Frail elderly (mean age 82.5) undergoing 16 weeks of WBV showed clinically significant improvements on Timed Up and Go, Parallel Walk, and 10-meter walk tests, with benefits retained at 12-month follow-up (Wadsworth & Lark, 2020).
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Nursing home residents experienced 2.4–3.5 point improvements on balance-related scales and an 11-second reduction in Timed Up and Go times after WBV (Bruyère et al., 2005).
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Gait and balance across mixed clinical populations
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A large systematic review (Fischer et al., 2019) spanning elderly individuals, osteoarthritis, stroke, COPD, multiple sclerosis, cerebral palsy, and postmenopausal women found standardized mean differences ranging from –0.18 to 1.28 for gait and balance, generally favoring WBV for improved walking speed, balance, and neuromuscular function.
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Older adults with knee osteoarthritis
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WBV combined with squats improved Berg Balance Scale, Timed Up and Go, chair-stand test, 6-minute walk test, and WOMAC scores (Avelar et al., 2011).
Overall, WBV robustly enhances functional mobility and balance in older and clinical populations, supporting reduced fall risk and better independence.
4. Stress, Anxiety, and Mental Health
Although fewer in number, the available studies suggest that WBV can confer mental health benefits, particularly for stress, anxiety, and depression.
Evidence Summary
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College students (inactive)
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A 4-week RCT (2×/week WBV) in inactive students found significant reductions in depression, anxiety, and stress as measured by the Depression Anxiety Stress Scales (DASS) and improvements in SF-36 quality of life (Chawla et al., 2022).
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Fibromyalgia
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WBV plus exercise in fibromyalgia often improves fatigue, mood, and quality-of-life measures, with reductions in depression scores (e.g., Beck Depression Inventory) in some trials (Alentorn-Geli et al., 2008; Alev et al., 2017).
While the mental health evidence base is smaller than that for pain or function, results are consistently positive where assessed, especially when WBV is paired with exercise or rehabilitation programs.
5. Sleep and Recovery
Direct sleep outcomes are notably absent from the WBV literature included in this review.
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No studies directly measured sleep (e.g., polysomnography, PSQI, insomnia severity) as a primary endpoint.
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Some trials used quality-of-life instruments (e.g., SF-36) that include sleep/vitality domains, but these were not reported separately.
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One RCT (Rhea et al., 2009) documented reduced DOMS (22–61%), suggesting improved muscular recovery, which may indirectly support better sleep and restoration, but this remains speculative.
Given the lack of targeted sleep measures, no firm conclusions can be drawn about direct effects of WBV on sleep, and this represents a clear gap for future research.
6. Vitality, Quality of Life, and Longevity Markers
While no included study directly measured longevity, several assessed vitality, general health, and functional markers that connect to healthy aging.
Vitality & Quality of Life
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SF-36 and similar QoL instruments
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In older adults and nursing home residents, WBV improved SF-36 domains, including vitality, physical function, and general health.
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Women with fibromyalgia showed 5–9.8% improvements in Fibromyalgia Impact Questionnaire and SF-36 scores after WBV (Sañudo et al., 2010).
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Fibromyalgia Impact Questionnaire
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Multiple trials (Alentorn-Geli et al., 2008; Alev et al., 2017; Mingorance et al., 2021) report reduced disease impact and improved functional/vitality domains, though the persistence of gains varies between studies.
Longevity-Related Markers
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Direct measurements of lifespan, mortality, or biological aging markers are absent.
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However, WBV consistently improves:
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Strength, function, and balance – linked to lower fall risk and better survival in aging populations.
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Mobility and independence – key predictors of long-term health and healthcare utilization.
These suggest that WBV supports healthy aging trajectories, but causal links to longevity remain untested.
7. Safety, Adverse Effects, and Implementation
Safety and Adverse Events
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Across the included trials and reviews, WBV is generally well tolerated.
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Adverse events are rarely reported and, when mentioned, are minor; one systematic review (Remer et al., 2023) explicitly notes no adverse events.
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Underreporting of adverse events is possible, and authors highlight the need for more systematic safety reporting.
Implementation Considerations
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Accessibility & scalability
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WBV platforms can be deployed in clinics, rehabilitation centers, gyms, and potentially home settings.
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Protocols are typically short (5–15 minutes per session) and can be adapted for various ability levels.
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Adherence
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High adherence is frequently reported, particularly in structured programs within residential care or clinical environments.
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Integration with other therapies
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WBV is often combined with strength or functional exercises, which may enhance outcomes and mimic real-world rehabilitation protocols.
PART 4
Final Conclusion
Full-body vibration training is a promising, low-impact neuromuscular intervention with evidence supporting:
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Pain reduction in chronic musculoskeletal conditions such as knee osteoarthritis, chronic low back pain, and fibromyalgia, with moderate effect sizes and clinically meaningful improvements.
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Enhanced physical performance, including muscle strength, power, and endurance, especially in older adults and athletes.
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Improved balance, gait, and functional mobility, reducing fall risk and supporting independence in frail and elderly populations.
Positive mental health impacts in limited but encouraging studies, including reductions in depression, anxiety, and stress. -
Better quality of life and vitality, as captured by multi-domain instruments such as SF-36 and the Fibromyalgia Impact Questionnaire.
At the same time:
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No studies directly assess sleep, and
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No studies measure longevity or biological aging endpoints, though improvements in function, balance, and vitality likely support healthier aging overall.
The safety profile appears favorable, with minimal adverse effects reported and good adherence. Protocol heterogeneity (different frequencies, amplitudes, durations, and co-exercises) and incomplete reporting are the main limitations, alongside under-reporting of adverse events and limited data on mental health and cognitive outcomes.
Overall, the existing evidence supports full-body vibration as a safe, effective adjunct to conventional exercise and rehabilitation for:
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Reducing pain
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Enhancing strength and physical performance
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Improving mobility, balance, and quality of life
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Supporting mental well-being and perceived vitality
Future research should prioritize:
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Direct assessment of sleep outcomes and recovery
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Long-term follow-up on fall risk, disability, and mortality
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Standardization of WBV protocols and systematic safety reporting
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More rigorous trials on stress, anxiety, and cognitive performance
References
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Alp Alev et al. “Effects of Whole Body Vibration Therapy in Pain, Function and Depression of the Patients with Fibromyalgia.” Complementary Therapies in Clinical Practice, 2017.
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An Bogaerts et al. “Impact of Whole-Body Vibration Training Versus Fitness Training on Muscle Strength and Muscle Mass in Older Men: A 1-Year Randomized Controlled Trial.” Journals of Gerontology Series A, 2007.
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B. Sañudo et al. “The Effect of 6-Week Exercise Programme and Whole Body Vibration on Strength and Quality of Life in Women with Fibromyalgia: A Randomised Study.” Clinical and Experimental Rheumatology, 2010.
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Chen Guang Qiu et al. “Effects of Whole-Body Vibration Therapy on Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Journal of Rehabilitation Medicine, 2022.
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D. Wadsworth & S. Lark. “Effects of Whole Body Vibration Training on the Physical Function of the Frail Elderly: An Open, Randomised Control Trial.” Archives of Physical Medicine and Rehabilitation, 2020.
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Eduard Alentorn-Geli et al. “Six Weeks of Whole-Body Vibration Exercise Improves Pain and Fatigue in Women with Fibromyalgia.” Journal of Alternative and Complementary Medicine, 2008.
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F. Fagnani et al. “The Effects of a Whole-Body Vibration Program on Muscle Performance and Flexibility in Female Athletes.” American Journal of Physical Medicine & Rehabilitation, 2006.
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Franziska Remer et al. “Effects of Whole-Body Vibration Therapy on Pain, Functionality, Postural Stability, and Proprioception in Patients with Subacute and Chronic Non-Specific Low Back Pain: A Systematic Review.” Wiener Medizinische Wochenschrift, 2023.
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Geetanjli Chawla et al. “Effect of Whole-Body Vibration on Depression, Anxiety, Stress, and Quality of Life in College Students: A Randomized Controlled Trial.” Oman Medical Journal, 2022.
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H. Zafar et al. “Therapeutic Effects of Whole-Body Vibration Training in Knee Osteoarthritis: A Systematic Review and Meta-Analysis.” Archives of Physical Medicine and Rehabilitation, 2015.
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Hyun Joo Kim et al. “The Impact of Whole-Body Vibration Training on Lower-Extremity Muscle Function in Older Adults: A Systematic Review and Meta-Analysis.” International Journal of Applied Sports Sciences, 2023.
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J. Mingorance et al. “The Therapeutic Effects of Whole-Body Vibration in Patients With Fibromyalgia. A Randomized Controlled Trial.” Frontiers in Neurology, 2021.
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M. Fischer et al. “Long-Term Effects of Whole-Body Vibration on Human Gait: A Systematic Review and Meta-Analysis.” Frontiers in Neurology, 2019.
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M. Rhea et al. “Effect of iTonic Whole-Body Vibration on Delayed-Onset Muscle Soreness Among Untrained Individuals.” Journal of Strength and Conditioning Research, 2009.
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N. C. Avelar et al. “The Effect of Adding Whole-Body Vibration to Squat Training on Functional Performance and Self-Report of Disease Status in Elderly Patients with Knee Osteoarthritis: A Randomized, Controlled Clinical Study.” Journal of Alternative and Complementary Medicine, 2011.
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N. Maeda et al. “Effect of Whole-Body-Vibration Training on Trunk-Muscle Strength and Physical Performance in Healthy Adults: Preliminary Results of a Randomized Controlled Trial.” Journal of Sport Rehabilitation, 2016.
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Najmeh Shadloo et al. “A Comparison Between Whole-Body Vibration and Conventional Training on Pain and Performance in Athletes with Patellofemoral Pain.” Journal of Bodywork & Movement Therapies, 2021.
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O. Bruyère et al. “Controlled Whole Body Vibration to Decrease Fall Risk and Improve Health-Related Quality of Life of Nursing Home Residents.” Archives of Physical Medicine and Rehabilitation, 2005.
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O. Bruyère et al. “Controlled Whole Body Vibrations Improve Health Related Quality of Life in Elderly Patients.” 2003.
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Pu Wang et al. “Effects of Whole Body Vibration on Pain, Stiffness and Physical Functions in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis.” Clinical Rehabilitation, 2015.
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Saila Torvinen et al. “Effect of Four-Month Vertical Whole Body Vibration on Performance and Balance.” Medicine & Science in Sports & Exercise, 2002.
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T. Furness & W. Maschette. “Influence of Whole Body Vibration Platform Frequency on Neuromuscular Performance of Community-Dwelling Older Adults.” Journal of Strength and Conditioning Research, 2009.
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Xiaohuan Tan et al. “Effects of Whole-Body Vibration Training on Lower Limb Muscle Strength and Physical Performance Among Older Adults: A Systematic Review and Meta-Analysis.” Archives of Physical Medicine and Rehabilitation, 2023.
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Xue-Qiang Wang et al. “Effects of Whole-Body Vibration Exercise for Non-Specific Chronic Low Back Pain: An Assessor-Blind, Randomized Controlled Trial.” Clinical Rehabilitation, 2019.
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Yulin Dong et al. “Whole Body Vibration Exercise for Chronic Musculoskeletal Pain: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.” Archives of Physical Medicine and Rehabilitation, 2019.





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